Oct3/4, Sox2, Klf4, c-Myc

What are the strange alphanumeric expressions in the title of this post?

Are they stock numbers?

Perhaps the key to cornering the market?

No. They’re human genes, but they are–potentially–the solution to a raging social issue: the embryonic stem cell debate.

Writing in The Weekly Standard, Ryan Anderson–an assistant editor at First Things–states:

The stem cell wars are over. Leading scientists are telling us that they can pursue the most promising stem cell research without using–much less killing–human embryos. This breakthrough enables researchers to create human embryonic stem cells directly from adult cells. In fact, the new method may actually prove superior to embryo-destructive alternatives. This is the biggest stem cell advance since James Thomson became the first scientist to isolate embryonic stem cells, less than a decade ago.

It is a new study by Thomson himself that has caused the present stir, but this time Thomson is not alone. Accounts of independent research by two separate teams of scientists were published on November 20–one in the journal Cell and one in the journal Science–documenting the production of pluri-potent human stem cells without using embryos or eggs or cloning or any morally questionable method at all.

The new technique is so promising that on November 16, Ian Wilmut announced that he would no longer seek to clone humans. Wilmut, you may remember, is the scientist who cloned Dolly the sheep. He recently sought and received a license from the British government to attempt to clone human embryos for research purposes. Now, citing the new technique, he has abandoned his plans.

Now, I’ve head prospective ways of creating pluripotent stem cells without embryos before–and I haven’t been convinced that they were what they were said to be. The ones I’ve heard before struck me as ways of creating, or potentially creating, severely deformed human embryos and harvesting their stem cells, so I’m skeptical of new miracle procedures that will get around the problem.

I’d like to learn more about the technique that Anderson writes about, but from the description he gives of it in his Weekly Standard article, it sounds as if we may have the genuine article here.

The idea is that you take adult cells and–rather than turning them into totipotent stem cells, which could conceivably be an embryo under another name, you reprogram only select genes in them–those in the article title–and you get a pluripotent-but-not-totipotent stem cell directly from an adult cell.

If that’s what’s really happening in this technique, we may–indeed–have a solution to the stem cell wars.

If so, we have a cause for rejoicing.

READ THE WHOLE THING.

Rome Really Needs To Get Involved on This One

The U.S. bishops continue to hold diverse opinions about whether or not canon law requires one to withhold Communion from pro-abortion politicians.

Many, out of an apparent desire not to alienate those who hold pro-abortion views–as part of a "woo them back gently" strategy–resist the idea that Communion should be withheld from such politicians.

The replies given by some bishops involve arguments that strike one variously as (a) dodges of the real issue, (b) subversive of canon 915, or (c) simply incoherent.

For the record, canon 915 states:

Can.  915 Those who have been excommunicated or interdicted after the imposition or declaration of the penalty and others obstinately persevering in manifest grave sin are not to be admitted to holy Communion.

This is the Church’s law. Yet some quotes from bishops in the media give the appearance that the respective bishops have never heard of this canon, which is difficult to believe after the "Can John Kerry receive Communion?" controversy of the 2004 election.

Part of the problem we are encountering at present is that bishops do not like to be pitted against each other in the press and, since there is not a consensus among them about whether canon 915 should be applied to the case of pro-abortion politicians, many are engaging in diplomatic contortions to avoid bringing the disagreement among them into sharp public focus on the eve of an election season.

So we have a significant disagreement among Church leaders on how the Church’s law is to be applied.

Well, that’s why God created the Pontifical Council for the Interpretation of Legislative Texts.

We need an authentic interpretation on this point–one way or the other.

For myself, I am strongly of the opinion that both canon and moral law require the withholding of Communion from a politician with a pro-abortion voting record (even if it’s with an "I’m personally opposed, but" dodge).

But Rome needs to sort this out for the good of the Church–both here in American and wherever in the world abortion is being promoted, which includes Rome’s own back yard: Europe.

It’s time for the Church to take a stand on this, for as canonist Ed Peters writes:

We are living through a terrible, perhaps unprecedented, unraveling of respect for Jesus in the Eucharist. Such a crisis compels all of us, I think, to examine our consciences for how our sins might have contributed to this disaster.

GET THE STORY.

Bad News In Connecticut–Part II

In my prior post, I mentioned that I’ve received multiple requests for comment on the Connecticut Plan B situation. The following reader expresses the sentiments of many when he writes:

Jimmy,

What is going on in Connecticut right now?  The Bishops there have
released a statement, explaining that they will now allow Plan B to be
administered in their hospitals…where they previously stated (or
implied) otherwise.  Curt Jester & American Papist have coverage on
this, but I just don’t understand the issue.

Specifically, why is contraception allowed after rape (since it’s
sex without the proper intent etc etc) but is NOT permitted after
casual, recreational sex that also lacks the proper intent?

It’s understandable, given the Church’s strong stand against contraception and abortion, why this issue would be so confusing. In order to make sense of it, we need to look at several things, but first

THE BIG RED DISCLAIMER: What I am about to write is not indicative of my own view. I’m trying to explain the apparent reasoning of the Connecticut bishops. I’m not saying that they are correct or incorrect. Rome could rule either way on this, and it may well get involved. What I’m trying to do is explain a position, not defend it.

The starting point to understanding the apparent reasoning behind the Connecticut bishops’ statement is a close reading of Pope Paul VI’s encyclical, Humanae Vitae. Here’s the key line in Latin:

Item quivis respuendus est actus, qui, cum coniugale commercium vel
praevidetur vel efficitur vel ad suos naturales exitus ducit, id tamquam finem
obtinendum aut viam adhibendam intendat, ut procreatio impediatur.

Now, I’ve given this in Latin so that you can see the key term coniugale commercium. Coniugale means "conjugal/marital/pertaining to or proper to marriage." Commercium means "commerce/traffic/relations/intercourse/sexual intercourse."

You could translate this literally as "conjugal intercourse," "conjugal relations," "marital intercourse," "marital relations"–things of that nature.

Which is how this passage is translated when it’s quoted in the Catechism:

2370 Periodic continence, that is, the methods of birth regulation based on self-observation and the use of infertile periods, is in conformity with the objective criteria of morality. These methods respect the bodies of the spouses, encourage tenderness between them, and favor the education of an authentic freedom. In contrast, "every action which, whether in anticipation of the conjugal act, or in its accomplishment, or in the development of its natural consequences, proposes, whether as an end or as a means, to render procreation impossible" is intrinsically evil

Unfortunately, some translators are sloppy in how they handle this text (which is particularly unfortunate, since it’s a key text in a sensitive document). For example, the English translation of HV on the Vatican web site renders this:

Similarly excluded is any action which either before, at the moment of, or after sexual intercourse, is specifically intended to prevent procreation—whether as an end or as a means.

That’s a loosey-goosey translation, and if you go with that one, what the Connecticut bishops said will be absolutely inexplicable, since the use of Plan B to prevent ovulation or fertilization clearly would be "specifically intended to prevent procreation . . . as an end . . . after sexual intercourse" (rearranging the elements of the quote a bit).

But that’s not what the Latin original says. It doesn’t say "sexual intercourse," it says "conjugal intercourse" and "conjugal" means "marital."

Paul VI phrased himself very carefully in this area, and what he did
was say that you can’t use contraception to thwart the procreative
aspect of marital intercourse. His language does not explicitly
address the issue of the procreative aspect of intercourse
outside of marriage.

Of course, intercourse outside of marriage always involves grave sin to begin
with, and it seems reasonable to conclude that if contraception in
marriage is an evil, contraception outside of marriage only compounds
the evil of non-marital sex. One day the pope or the Congregation
for the Doctrine of the Faith may clarify that this is indeed the case.

But this goes beyond what can be shown from the language of HV. The way HV is phrased
in the original Latin (and in the literal translation of the passage
given in the Catechism), all you can say with certainty is that Paul VI
condemned all use of contraception within marriage.

He did not address–or cannot be ascertained certainly as addressing–the situation of sexual relations outside of marriage.

Thus, some have held that at least some forms of contraception (ones
that aren’t abortifacient, for example) might not compound the evil of
non-marital sex. Some might argue that, although non-marital sexual acts are gravely wrong,
contraceptive non-marital sex might be less gravely wrong than non-contraceptive non-marital sex since it has a lesser risk of bringing a child into the world outside of wedlock.

By divine law, children have a right to be conceived only within a
family that has a father and a mother who are married to each
other. To the extent that they may cause children to be conceived
outside of wedlock, non-marital sexual acts can be viewed as grave sins against
charity regarding the child that may be conceived, as well as other
affected parties (such as innocent spouses).

In case of rape, one pursuing this line of argument might maintain, there is no sin in the victim using at least certain forms of contraception since the victim is not married to the rapist (apart from cases of marital rape) and did not consent to the sexual act.

Thus the U. S. bishops Ethical and Religious Directives for Catholic Health Care Services (4th ed.) states:

Compassionate and understanding care should be given to a person who is
the victim of sexual assault. Health care providers should cooperate
with law enforcement officials and offer the person psychological and
spiritual support as well as accurate medical information. A female who
has been raped should be able to defend herself against a potential
conception from the sexual assault. If, after appropriate testing,
there is no evidence that conception has occurred already, she may be
treated with medications that would prevent ovulation, sperm
capacitation, or fertilization. It is not permissible, however, to
initiate or to recommend treatments that have as their purpose or
direct effect the removal, destruction, or interference with the
implantation of a fertilized ovum
[n. 36].

The issue of non-marital contraception is a theological hot potato that the Holy See will eventually have to sort out, because this issue is not going to go away, as the situation of the Connecticut state law illustrates.

But if–and note the "if"–the Church ended up endorsing the view that contraception is impermissible within marriage but potentially permissible outside it then it would allow for a variety of situations, such as:

  • Nuns in dangerous situations where they may be raped could use at least some forms of contraception

  • Women who have been raped could be given at least some forms of contraception

I’m not defending these views. I’m just pointing out that they are not expressly precluded by the language used in Humanae Vitae or, to my knowledge, by subsequent Magisterial documents.

You might find the above line of reasoning entirely implausible, but I’m not advocating it. I’m merely trying to help with the "What on earth are they thinking?" factor of this situation.

If you are of the opinion that the above views are wrong, you might well conclude that the Holy Spirit will prevent the Church from ever endorsing such views and that he may guide the Church into a clear-cut rejection of those views.

But that has not yet occurred, at least in Magisterial documents that I am aware of.

In fact–and this is pure speculation and should not be taken as anything other than the pointing out of a possibility–the Connecticut bishops may even have consulted with the CDF for advice about how to handle this issue.

That leaves the question of whether the policy they announced is a good one, and, speaking only for myself, I can only say that I find the announced policy to be troubling.

There are disputed claims about whether Plan B will prevent the implantation of a newly-conceived child. The manufacturer’s own label for the product (see links to American Papist and Curt Jester) say that it may have this effect. Legal disclaimers of this nature are notoriously broad–in order to prevent future lawsuits–and they frequently list potential outcomes for the use of drugs that are either not possible with the drug in question or which are very unlikely. Because of this kind of language in medical disclaimers, as well as a lack of knowledge about how Plan B actually works, there is ambiguity about whether or not it is abortifacient.

That ambiguity is what generates a lot of the tension within the Connecticut bishops’ statement, and it is one of the things that I find troubling about the whole situation.

I’m far from being an expert on Plan B, but any time there is a possibility that something is abortifacient, I want to apply the Deerhunter Principle: If you’re out in the woods hunting, you cannot open fire if the result is reasonably foreseen to involve the possible death of a human.

Bad News In Connecticut

The recent statement by the Connecticut bishops that they will allow Plan B to be used for rape victims in Catholic hospitals is causing a great deal of consternation in the Catholic community, and I have received numerous requests for help in figuring out what is going on.

I’ll do my best to help, but let’s begin with some background.

FIRST, HERE IS AMERICAN PAPIST SUMMARIZING WHAT HAS HAPPENED SO FAR.

AND HERE’S COVERAGE BY THE CURT JESTER.

Some of the early coverage of this was hampered by the fact that the statement of the Connecticut bishops did not seem to be on their web site, making it hard for people to know what they said without the lens of the news media.

The statement is now there, but it’s in a Word doc, so here’s the full text of it in html:

—————————————————


Connecticut Bishops Statement On
Plan B and Catholic Hospitals

Issued September 27, 2007

The Catholic Bishops of Connecticut, joined by the leaders of the Catholic hospitals in the State, issue the following statement regarding the administration of Plan B in Catholic hospitals to victims of rape:

The four Catholic hospitals in the State of Connecticut remain committed to providing competent and compassionate care to victims of rape. In accordance with Catholic moral teaching, these hospitals provide emergency contraception after appropriate testing. Under the existing hospital protocols, this includes a pregnancy test and an ovulation test.  Catholic moral teaching is adamantly opposed to abortion, but not to emergency contraception for victims of rape.

This past spring the Governor signed into a law “An Act Concerning Compassionate Care for Victims of Sexual Assault,” passed by the State Legislature. It does not allow medical professionals to take into account the results of the ovulation test. The Bishops and other Catholic health care leaders believe that this law is seriously flawed, but not sufficiently to bar compliance with it at the present time. We continue to believe this law should be changed.

Nonetheless, to administer Plan B pills in Catholic hospitals to victims of rape a pregnancy test to determine that the woman has not conceived is sufficient.  An ovulation test will not be required.  The administration of Plan B pills in this instance cannot be judged to be the commission of an abortion because of such doubt about how Plan B pills and similar drugs work and because of the current impossibility of knowing from the ovulation test whether a new life is present.  To administer Plan B pills without an ovulation test is not an intrinsically evil act.

Since the teaching authority of the Church has not definitively resolved this matter and since there is serious doubt about how Plan B pills work, the Catholic Bishops of Connecticut have stated that Catholic hospitals in the State may follow protocols that do not require an ovulation test in the treatment of victims of rape. A pregnancy test approved by the United States Food and Drug Administration suffices. If it becomes clear that Plan B pills would lead to an early chemical abortion in some instances, this matter would have to be reopened.

—————————————————

Commentary later.

Lying Liars and the Lies They Tell

A reader writes:

I don’t know if you saw Dr. Phil tonight, but he was doing a show about liars.  The first guy was incredible– he had absolutely no clue.  He impersonated all kinds of things — including a Roman Catholic priest!  He posed as a "visiting priest from Mexico," heard an engaged couple’s confessions, performed their wedding, and faked the mass.  I can’t tell you how flabbergasted I was.  It is obvious that this guy is completely unrepentant.

But, here is my question– Where does that leave the couple?  Obviously, they were not legally married by this fraud, the mass cannot possibly be valid, and he violated the sanctity of the confessional as well.

But what about the couple who believed in good faith that they were married?  The marriage can be convalidated, I guess.  But am I correct in assuming that there was no sin of fornication in this instance?  They did not know about this bogus "Fr. Fred" until they returned from their honeymoon.

I am so bowled over by the audacity and callousness of what he did to this couple and to other victims, my brain is fried.  He actually terms himself "a benevolent con man" and doesn’t think it was wrong, because he "worked and earned a living" by impersonating everything from a psychiatrist to a orchestral conductor.

Like I keep saying, I don’t get it.  I would appreciate your comments.

Reports of this type are, indeed, disturbing, and to do what this man did is clearly a grave sin against the people he deceived. If the gentleman was Catholic, he would be subject to multiple penalties under canon law.

In terms of where he left the couple that he purported to marry, you are correct that there is not a valid marriage between them and they would need to have that situation fixed in order to go on living together as husband and wife.

In terms of the moral character of their life as husband and wife prior to the point at which they learned the priest was a fake, they were acting in good conscience. This does not mean that they were not performing acts that were objectively immoral (having sexual relations with a person to whom you are not married) but the fact that they did not know that this was the case means that they are not culpable for engaging in those acts.

This illustrates why the man in question was not a "benevolent con man." He deceived a couple into engaging in objectively gravely immoral acts, and that is gravely sinful even if the couple was acting in good conscience.

Incidentally, this kind of thing–simulation of the sacraments by a fake priest–is precisely what makes me uncomfortable with the concept of movies like The Left Hand of God or TV shows like Father Murphy.

New CDF Document! New CDF Document! New CDF Document!

“The chances of an elderly person in this condition with septic shock surviving 24 to 48 hours are slim — about 10-20 percent, but that would be in an intensive care unit with very aggressive treatment,” said Dr. Gianni Angelini, a professor of cardiac surgery at Bristol University in England.

“If he is not going back to the hospital, they must realize there’s not much point in doing anything more heroic. It indicates they are preparing for him to die peacefully at the Vatican,” Angelini said.
“The chances of an elderly person in this condition with septic shock surviving 24 to 48 hours are slim — about 10-20 percent, but that would be in an intensive care unit with very aggressive treatment,” said Dr. Gianni Angelini, a professor of cardiac surgery at Bristol University in England.

“If he is not going back to the hospital, they must realize there’s not much point in doing anything more heroic. It indicates they are preparing for him to die peacefully at the Vatican,” Angelini said.

This has nothing to do with feeding and hydration. Why is it that those advocating we let people starve to death can not honestly recognize the difference that that the Church instructs us to recognize? The document clearly explains it.
God Bless,
Matt

I like new CDF documents!

They make me happy.

I have a whole book of them (mostly in Latin and other non-English languages, unfortunately), of all the CDF documents from Vatican II through the end of John Paul II’s reign.

I expect to be especially happy when the new bioethics document they’re working on comes out.

The current document gives us a preview of a topic they may take up in the forthcoming one. The current document consists of a pair of responses to dubia submitted regarding whether you can yank artificially administered food and water from someone in a "vegetative state."

And the answer is . . .

.

.

.

.

.

SPOILER SPACE

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.

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.

.

No! You can’t starve someone to death just because they have impaired mental abilities or have lost consciousness!

So there!

Take that, Evil Medical Establishment!

There are, of course, cases when the administration of food or water actually harms the patient (because the body has lost the ability to assimilate them), but that’s a different situation. It isn’t the case that just because someone’s lost mental function that it’s okay to starve them to death.

HERE’S THE DOCUMENT. [Evil File Format: .pdf warning!]

Oddly, it was released with an unsigned commentary amplifying on the responses. That’s something the CDF has taken to doing in some cases lately, which is kinda weird since the commentary has ambiguous doctrinal status, but it seems to be a mode of operation the body is trying out. Such commentaries seem to have a status of "not official Church teaching, but trying to help explain official Church teaching and the reasons for it."

AND HERE’S SOME COMMENTARY ON THE RESPONSES AND THE COMMENTARY FROM THE NATIONAL CATHOLIC BIOETHICS CENTER.

P.S. Goat stealing is also immoral, but the new CDF document doesn’t go into that. Maybe a future one will.

UK Embryo Horror

Hybrid_embryo_processYou may have seen press stories recently about UK scientists pleading for the use of hybrid human-animal embryos in stem cell research.

Now the British press is reporting that it looks like the plan will be given the go-ahead.

If this were a matter of just splicing a few human genes into a clearly non-human organism, matters would be different, but it appears that the plan involves the creation of an organism that is 99.9% human (see diagram, left).

Basically, they’re talking about eliminating the nuclear genetic information in an animal (most likely cow) cell and shoving in the nucleus of a human cell, then stimulating the result to develop into an embryo.

It’s true that there is non-nuclear genetic material that is found in cells–in organelles besides the nucleus. For example, you may have heard of mitochondrial DNA (DNA found in the mitochondria, which are not part of the nucleus). The process as described would appear to leave that genetic material intact from the animal providing the ovum.

But I’m sorry, this really looks like creating a human being that has a slight admixture of cow genes, not creating a cow that has a slight admixture of human genes.

As a result, one must err on the side of caution and conclude that such embryos are human beings with the right to life and the British government is planning on murdering them or funding their murder.

The stories in the British press cite polling done of people suggesting that the British public favors the use of embryos in trying to find cures for Parkinson’s and Altzheimer’s.

I bet the pollsters didn’t ask, "Are you in favor of research that involves killing something that might be a human being and that in fact has 99.9% human genetic material."

GET THE STORY.

HERE TOO.

Go, Arkansas!

CNS reports:

Staten Island, Aug 2, 2007 / 11:06 am (CNA).- Abortion clinics nationwide should be required to post a sign stating that women cannot be forced into having an abortion, say the founders of the Silent No More Awareness Campaign, the nation’s largest network of women hurt by abortion.

Co-founders Georgette Forney and Janet Morana, believe the law should be based on a newly adopted measure in Arkansas, which requires abortion businesses to post a sign stating that women cannot be forced to have an abortion.

"I can’t tell you how many women I know who’ve been pressured into aborting by a boyfriend, husband, or parent," said Forney.

"This Arkansas statute is really just a gentle reminder to women that no one has the right to threaten or intimidate us into terminating our children,” she continued. “Everyone in every state should support this type of legislation. After all, how could someone who says he’s pro-choice oppose a law that tells a woman she has a choice?"

Janet Morana said the law is needed because abortion clinics have a financial interest in women having abortions and would not post such a sign on their own.

SOURCE.